The API’s are manufactured from raw materials through both chemical and physical means.
The API is the basic drug itself with the desired medicinal (pharmaceutical or pesticide)
properties. It is also referred to as Bulk drugs and the term active substance may be used
for natural products.
The API’s are defined as per world health organization guidelines in a following way
Any substance or combination of substances used in a finished pharmaceutical product
(FPP), intended to furnish pharmacological activity or to otherwise have direct effect in the
diagnosis, cure, mitigation, treatment or prevention of disease, or to have direct effect in
restoring, correcting or modifying physiological functions in human beings